Peter Parker/Spider-Man: Blessed with extraordinary intelligence, Peter Parker was a stereotypical nerd. All of that changed after being bitten by a radioactive spider. Now gifted with agility, speed, and the proportional strength of a spider, Peter fights crime as Spider-Man, living by the motto of his late Uncle Ben: "With great power comes great responsibility." Now, he faces his toughest challenge yet: college!

Victor Cranston: Peter's best friend and roommate just happens to be another superhero, the Shadow. Victor is the third generation to take the mantle, but the first to naturally have the powers of mild telepathy and invisiblity. He just recently learned how his father's career ended.

Mary Jane Watson: After Peter saved her life during an attack at the diner she worked at, these two became very close friends. Not long after that, they took their relationship to the next level, and Peter revealed his alter ego. However, both Peter and Mary Jane are starting to notice how Spider-Man is starting to get the way of their relationship, but are afraid to admit it to each other . . . or themselves.

Gwen Stacy: She certainly knew how to make a great first impression on her first day at ESU that few guys would ever forget. A star science student, Gwen is giving Peter a run for his money in the brains department. Is it just the foundation of a great friendship, or is it more?

Jason Todd: One of the only high school friends of Peter and Victor to make the jump with them to college. Jason helps keep the guys' heads in the game of college, and makes sure that they're enjoying every moment they can.

Richard Parker: Father of Peter, agent of SHIELD, he was supposedly killed in a car accident shortly after Peter's birth. However, recent discoveries have led Peter to believe that he was not killed.

Mary Parker: Mother of Peter, agent of SHIELD, she was also believed to have died in a car accident. However, there is evidence that she may not have died, or at least not when and how she was said to have died.